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Daratumumab has direct and indirect anti-cancer activity by binding to CD38, inducing direct apoptosis of tumor cells and triggering complement-dependent cytotoxicity (CDC), antibody-dependent cell-mediated cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP) [64]

Therefore, we established an alternative CPZ mouse model by oral gavage with the optimal dose of 400 mg/kg to induce demyelination and withdrawing CPZ to induce remyelination 18

Selective estrogen receptor modulation: concept and consequences in cancer

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(2) For a Part B rebatable drug previously billed under a grouped billing and payment code during the payment amount benchmark quarter and later billed under a unique billing and payment code, CMS will use the grouped billing and payment code payment limit as the payment amount in the payment amount benchmark quarter