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The underlying causes of metabolic injury are most likely highly individual, and comprise an interrelated portfolio of genetic susceptibility and triggers from the luminal environment, including diet and the microbiome 10,177,178,179,180

Additionally, apoptotic neutrophils and thymocytes exhibited similar lipidomic features, and their efferocytosis resulted in a higher accumulation of free fatty acids (FFAs) in macrophages, as well as the upregulation of genes associated with pathways activated by fatty acids and cholesterol, including PPAR and LXR

Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis

I think it's interesting, because I never thought that would be the case, but it's also a good example of how human beings are complex creatures, and to try to define someone by any one thing -- be it race, religion, athletic ability, or sexuality -- is doing a disservice to how wonderfully diverse humanity really is

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