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Conditions persisting six months or longer have established dysfunctional tissue patterns that take longer to remodel

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268 When activated, the vagus nerve can reduce the contraction of the stomach, thereby slowing down food emptying

Studies indicate that A1AT therapy can lead to a reduction in systemic inflammation, as measured by lower CRP levels, thus potentially decreasing the overall inflammatory burden on the lungs (68) Moreover, the reduction in inflammatory markers can also be indicative of the therapys effectiveness in mitigating the proteolytic damage caused by neutrophil elastase, which is typically unopposed in AATD patients due to low A1AT levels

Autoimmune thyroid disease represents a risk of Hashimotos thyroiditis and Graves disease (Franco et al