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Description

Decreased levels of nitrosothiols in the lower airways of patients with cystic fibrosis and normal pulmonary function

Jimenez C, Melin B, Koulmann N, Allevard AM, Launay JC, Savourey G

10.1210/endo.138.10.5453 Endocrinology 130 VillaE.MarchettiS.RicciJ

This transporter effectively imports oxidized glutathione (GSSG) into the ER while exporting the reduced variant (GSH), thereby fine-tuning the oxidative ratio inside the lumen