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6H, black arrowheads)

Acknowledgements We thank Rosa Ferrentino and Marchesa Bilio for expert laboratory assistance

doi: 10.1016/j.jphs.2021.09.008 131 LiZJDaiHQHuangXWFengJDengJHWangZXet al

While persistent (albeit at low rates) HIV replication in the brain may be responsible for neurocognitive alterations observed in infected individuals, the toxicity of anti-retroviral drugs is also likely to contribute to neurodegenerative disorders in HIV patients