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Pleiotropic ZIP8 A391T implicates abnormal manganese homeostasis in complex human disease

In patients with Leber's disease, administration of cyanocobalamin may cause acute and rapid atrophy of the optic nerve

Journal of Toxicology

Under-the-Tongue Tablets or Sprays : Sublingual B12 dissolves under the tongue, offering a convenient option for those with absorption issues or difficulty swallowing pills, and research supports its effectiveness[22]