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It is deliberately membrane-permeable, which is what lets it get inside cells and act on an intracellular enzyme

Ferritin: A Multifunctional Nanoplatform for Biological Detection, Imaging Diagnosis, and Drug Delivery

These include: Swelling and redness at the injection site Localized tenderness or bruising Temporary unevenness as filler breaks down at different rates Patients should be reassured that these effects are expected and usually resolve within a few days