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May James, M

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However, after 40 h, citric acid concentration increased again, particularly in cultures with P

Statements Author contributions T-BC: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Writing original draft

One possible explanation for the increase in NR2B-containing NMDA receptor expression in HD models is that an extended polyglutamine repeat in htt decreases its binding to PSD95, a postsynaptic density protein involved in NMDA and kainate receptor clustering, leading to increased interaction of PSD95 with the NR2B subunit (Sun et al., 2001