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GSH synthesis occurs in two ATP-dependent enzymatic steps, starting with -glutamylcysteine formation, followed by its conversion to GSH, facilitated by GSH synthetase

Wedelolactone inhibits caspase-1/11 activation and reduces IL-1 and gasdermin D levels, thereby alleviating pyroptosis, ferroptosis, and lung injury through glutathione peroxidase-4 (GPX4) mediation [106]

Cannabis and test drugs were administered daily via subcutaneous route for one month and observations were done three times weekly

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1419) (dissolved in saline, in dose and application regimens as described before (for review see, i.e., [3,4,5,6,7,8,9,10,11,12,13,14,15,16,17])