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Description

ES cells require these 1-carbon units to produce H3K4me3 and remain undifferentiated

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Grgic, T., Banic, T., & Sikiric, P

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These encompass the maintenance of iron homeostasis, the metabolic process of cysteine, the activity of GPX4, the synthesis of polyunsaturated fatty acids (PUFA), the regulatory role of nuclear factor E2-related factor (NRF2), the function of the tumor suppressor protein p53, the protective mechanism of heat shock proteins (HSPs), the regulatory role of iron regulatory inhibitor-1 (FSP1), the activation state of AMP-activated protein kinase (AMPK), and the supply of nicotinamide adenine dinucleotide phosphate (NADPH)

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The 2-fold enrichment of the amino acid superpathway metabolites (23% of known metabolites are amino acids) could indicate a differential rebalancing of amino acids during the 24-hour recovery period in participants with ME/CFS compared with controls, especially from the leucine, isoleucine and valine metabolism as well as the arginine and proline metabolism pathway

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Ursodeoxycholic acid versus placebo in the treatment of women with intrahepatic cholestasis of pregnancy (ICP) to improve perinatal outcomes: protocol for a randomised controlled trial (PITCHES)

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