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Description

Vascular Degeneration in Parkinsons Disease

The downregulation of SOD and upregulation of genes like MPO and HIF1 support this oxidative stress-driven mechanism

For this experiment, activated HL-60 cells were transfected with scramble siRNA (control), FPR1 siRNA or CXCR1 siRNA for 3 days and then the cells were co-incubated with His-tagged N0362 for 2 h