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This dual-protection approach inherent peptide stability combined with formulation engineering represents a methodologically robust approach to oral peptide delivery research

Thus, we could not confirm any clear G4 structure-dependence for the ING2 5 UTR, raising the possibility that G4 formation is too weak to be detected by conventional G4 detection assays, or that these small molecules bind to non-G4 structures

Reconstituted solution exposed to room temperature for more than a few hours, or to direct heat or freeze-thaw cycles, should be discarded

Analyses stratified by diabetes status were also performed

That said, the clinical evidence in healthy populations is limited