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While ABCG2 did not influence the toxicity of the compounds, the presence of iron enhanced the protective effect of ABCC1 in A431 cells against DpC (RR: 7.3 vs RR(Fe): 8.9) and significantly increased it in the case of COTI-2 (RR: 15.8 vs RR(Fe): 61.5

Consistency is more important than timing, so taking it at the same time every day is recommended

Nature 630 , 493500 (2024)

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For most healthy adults, taking these supplements together does not cause side effects