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Description

Enhanced DNA repair is probably implicated in drug resistance to the drugs interacting with DNA, for example, to nitrosomethylurea or platinum derivatives

A.HowellsD

To study the interaction, 200 ng/l dsDNA incubated for 24 h at 37C, 100 rpm, in either absence or presence of 1 mM GSH at intrinsic pH or 1 mM GSH at neutral pH (7.2)