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Description

We propose that PYC, a pine bark polyphenol extract, can modulate the structure of gut microbial community to increase the expression of SCFAs, GABA and 5-HT targeting the gut-brain axis as well as regulating synaptic protein synthesis and promoting plasticity, thus becoming a powerful natural drug candidate for the treatment of NDDs

U.ZuberiA.FernandesJ

Juli 18

National Institute of Mental Health

Urban air pollution, chronic psychological stress, insufficient sleep, high alcohol consumption, certain medications, and the natural aging process are key factors