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1 - 13 Thus, a hypothesis is that BPC 157 (since it is formed constitutively in the gastric mucosa, stable in human gastric juice, along with significance of NO-synthase and the basal formation of NO in stomach mucosa, greater than that seen in other tissues) exhibits a general, effective competition to both L-arginine analogues (i.e., L-NAME) and L-arginine

Furthermore, downregulation of GPX4 via genetic deletion or chemical inhibition can lead to ferroptosis in T cells, while upregulation of GPX4 and genetic deletion of ACSL4 can suppress ferroptosis in CD8+ T cells (88, 89)

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Grimme, S

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