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and dysregulation of tryptophan-serotonin-kynurenine pathways

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Several case reports described the occurrence of life-threatening events associated with risperidone toxicity (serotonin syndrome, neuroleptic malignant syndrome, profound coma, extrapyramidal symptoms and late-onset angioedema) in patients with HIV treated with different ritonavir-boosted PIs [48, 65,66,67,68]

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