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As we have seen with GLP-1 drugs, once a therapy demonstrates both biological efficacy and real-world impact, adoption can accelerate very quickly. Whether through stem cell activation, immune modulation, reformulated legacy drugs, or regenerative medicine, the next generation of hair loss therapies is no longer chasing incremental improvement

Kanekura K, Ma X, Murphy JT et al (2015) IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions

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Researchers are still looking for its potential role in the treatment of certain diseases caused by oxidative stress

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