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CBD was obtained from a formulation containing 5 mg/ml of CBD (Cayman Chemicals, USA), and was further diluted in saline

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Sleep apnea occurs predominantly in middle-aged men and postmenopausal women and is associated with obesity and cardiovascular complications, including hypertension, while narcolepsy and idiopathic hypersomnia are chronic brain disorders with an onset at a young age (5)

(2) Despite the fact that both peptides have distinct mechanisms of action, they have been found to exhibit synergistic effects when used in combination