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In severe cases, the inflammation can result in the fusion of spinal vertebrae, further limiting mobility and causing chronic pain

Kynurenine/tryptophan ratio as a potential blood-based biomarker in non-small cell lung cancer

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Methods: In this phase 2a, randomized, double-blind, placebo-controlled, multicenter, dose-escalation proof-of-concept study, oral INT-787 will be administered to patients with a diagnosis of sAH, with a Model for End-Stage Liver Disease-Sodium (MELD-Na) score of 18-25