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The reported median time to first onset of RPED is 62 days for pemigatinib (Incyte Corporation, 2022) and 40 days for futibatinib (Taiho Pharmaceutical Co

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That is, xCT inhibitors may exhibit anticancer properties against cancer cells with elevated GLUT1 expression in a high-glucose tumor environment, whereas glucose deprivation blocks ferroptosis-induced cell death [18,19] [Figure 2B]

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