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For instance, exercises that apply controlled mechanical loading to the ACL can stimulate the activation of mechanotransduction pathways, promoting the synthesis of collagen and other ECM components to strengthen the ligament

These include boosting immunity levels, neutralizing the damaging action of the free radicals, delaying the aging process, maintaining the health of the skin tissues, and preventing cancer

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In addition, viral infection has been implicated in the pathogenesis of SS

This is important with organs such as the lung and liver, where organ function reduces quite drastically following resection, particularly in cases where large margins are required (Samadzadeh et al., 2021)