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hypothesis glutathione persister cells Targeting PPP1R15B and ATF4 axis in hepatocellular carcinoma: A novel strategy for overcoming lenvatinib-tolerant through GPX4-mediated ferroptosis induction Drug-tolerant persister cancer cells are

Name: hypothesis glutathione persister cells Targeting PPP1R15B and ATF4 axis in hepatocellular carcinoma: A novel strategy for overcoming lenvatinib-tolerant through GPX4-mediated ferroptosis induction Drug-tolerant persister cancer cells are
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Drug tolerant persister cancer cells are vulnerable to GPX4 inhibition Nature Frontiers Glutathione Peroxidase 4 as a Therapeutic Target for Anti Colorectal Cancer Drug Tolerant Persister Cells Drug tolerant persister cancer cells are vulnerable to GPX4 inhibition PMC Drug tolerant persister cells in cancer: the cutting edges and future directions Nature Reviews Clinical Oncology Vaccinia related kinase 2 inhibition elicits vulnerability of glutathione metabolism in pancreatic cancer Cell Death & Disease

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Katsiougiannis S et al (2023) Salivary gland epithelial cell in Sjgrens syndrome: metabolic shift and altered mitochondrial morphology toward an innate immune cell function

Glutathione has actually been shown to help stabilise and enhance the performance of other antioxidants such as vitamin C, even in low concentrations

Moreover, only a minority incorporates multi-omics approaches that might yield predictive biomarkers (577)

Further study showed that L-theanine could obviously increase the expression of Bcl-2 mRNA and protein, decrease the expression of Bax, a pro-apoptotic molecule, and decrease the phosphorylation of ERK1/2 and c-Jun NH2-terminal kinase (JNK1/2) MAPKs (87)