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Excessive iron loading increases the expression of M1-associated inflammatory mediators, including IL-6, TNF-, and IL-1, while suppressing M2 markers such as transglutaminase 2 (TGM2), so efficiently guiding polarization toward the pro-inflammatory M1 phenotype (97)

The American Academy of Family Physicians reports that about 50 percent of adults have low magnesium levels (2022)

When you stop supplementing, your body does not experience a "crash," but it does return to its natural baseline levels

2013 Oct;38(11):2220-30

DMs intimate link with oxidative stress, makes NS therapy relevant since it is a potent antioxidant that energizes the cells endogenous arsenal of antioxidant enzymes