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Consistent with this result, a negative association was observed between dietary copper intake and depression in two cross-sectional Japanese studies and a meta-analysis (Nakamura et al., 2019

Alves-Filho, J

Ann N Y Acad Sci 512:237247

According to this scenario, it is interesting to consider that NK cells probably control at least two different types of secretion machineries during their cytotoxic responses: one to supply bulk membrane lipids to make ruffled membranes, and the other for cytotoxic granule secretion