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At the enzymatic regulatory level, GPX4 activity can be directly inhibited by small molecules such as RAS-selective lethal 3 and ML162, while GSH production is blocked by buthionine sulfoximine (157)

doi: 10.1016/j.scitotenv.2020.143375

Downregulation of inflammatory mediators and cytokines Radiation causes damage to normal cells and tissues and produces many inflammatory mediators, which in turn induce radiation-induced inflammation

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