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Compared with other well-characterized medications, NMN therapy presents several specific limitations: 1

Although some of the natural ingredients used in these patches, such as berberine, have shown in some studies to slightly increase GLP-1 levels, regulate blood sugar levels and promote weight loss 8 , their efficiency through transdermal methods is not yet proven and needs to be studied further 3

87:319324 Imokawa G (1989) Analysis of initial melanogenesis including tyrosinase transfer and melanosome differentiation through interrupted melanization by glutathione