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Palmiter, R.D., Brinster, R.L., Hammer, R.E., Trumbauer, M.E., Rosenfeld, M.G., Birnberg, N.C., Evans, R.M

Simultaneous Fenton-like ion delivery and glutathione depletion by MnO(2) -based nanoagent to enhance chemodynamic therapy

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The high activity of 30 prompted a synthesis of the corresponding disulfide 32 with a 14-membered ring system anticipated be able to adopt a similar trans conformation as 30