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Taken together, these results support a model in which metformin suppresses TXNIP expression not through AMPK activation, but via mitochondrial complex I inhibition, leading to increased NADPH production, enhanced antioxidant gene expression and ROS reduction

Within the visual cycle, the regeneration of 11-cis-retinoic acid retinol (atRAL) between photoreceptors and the RPE is crucial for sustaining visual acuity (259)

Epigenetic mechanisms include DNA methylation, histone modification, and the presence of small non-coding ribonucleic acid (RNA) molecules such as micro-RNA (miRNA) that regulate the post-transcriptional expression of target genes in the oncogenic process [29]

Serotonin-induced hypoglycemia and increased serum insulin levels in mice

Use of corticoids and non-steroidal anti-inflammatories in the treatment of rheumatoid arthritis: systematic review and network meta-analysis