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In DCM, marked by chronic high-glucose and high-fat exposure, cardiomyocytes divert excess long-chain and very-long-chain fatty acids into peroxisomes for -oxidation as a compensatory relief valve, resulting in elevated H 2 O 2 production

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A total of 50 rats were systematically assigned into five distinct groups, encompassing control and treatment cohorts that received Rhodiola or fluoxetine over a duration of 3 weeks