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All electrons want to exist in pairs

Van Den Eeden SK, Tanner CM, Bernstein AL et al (2003) Incidence of Parkinsons disease: variation by age, gender, and race/ethnicity

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Figure 2 Cellular Processes Linked to Redox Imbalance That Are Dysregulated in Als Protein Misfolding The presence of misfolded proteins is known to induce oxidative stress