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Ethical approval This article does not contain any studies with human and/or animal participants performed by any of the authors

Activated Chk1/2 then phosphorylate and inhibit the phosphatase CDC25

-HB has been shown to exert neuroprotective effects on dopaminergic neurons [52], with consistent evidence from MPTP-induced models of PD, where it prevents the loss of dopaminergic cells in the substantia nigra [53]

As a novel iron chelating agent and oxidative phosphorylation inhibitor, VLX600 can induce non-caspase-dependent cell death in glioblastoma (GBM) cells (Reisbeck et al., 2023)