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doi: 10.1093/trstmh/trv103 [DOI] [PubMed] [Google Scholar] 35

doi: 10.1111/j.1365-2036.2011.04724.x 25 Arroyave-OspinaJCWuZGengYMoshageH

FOXO transcription factors play a crucial role in the regulation of processes related to aging and longevity, with increasing evidence suggesting their significance in the pathogenesis of neurodegenerative diseases (NDDs)

Mutations in human TLR4 have shown a higher incidence of Gram-negative infections in already immunocompromised patients compared to wild type (Wurfel et al., 2008)