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They demonstrated that this platform elevated extracellular ATP (eATP) levels, which triggered the activation of the P2X7-NLRP3-inflammasome to drive macrophage pyroptosis and potentiated the maturation and antigen capacity of DCs

If 1 mM or 15 mM carnitine was added before the omeprazole, surprisingly, the inhibition increased to 80% and 92%, indicating that the omeprazole reaction with the transporter was not protected but facilitated by the presence of carnitine

Zheng et al., 2025), has undergone an evolution in mechanistic understanding from the traditional lipid infiltration theory to a multi-omics regulatory network perspective (Moore et al., 2018)

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