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Exogenous supplementation of Monounsaturated Fatty Acid(MUFA), stearoyl-CoA desaturase (SCD1)-mediated cellular MUFA production, and Acyl-CoA Synthetase Long-Chain Family Member 3 (ACSL3)-dependent MUFA membrane enrichment have been reported to reduce the propensity of cells to die by ferroptosis (37).The main byproduct of lipid peroxidation is lipid hydroperoxides

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Regulation and removal of hydrogen peroxide prevents the formation of the highly reactive and damaging hydroxyl radical, which can be formed by reaction of hydrogen peroxide with Fe 2+ (Fenton reaction)

( h ) The levels of mRNAs encoding Myc and Rnd1 exhibit an inverse correlation in 3 breast cancer DNA microarray datasets