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Oral peptides, such as hydrolyzed collagen, are highly bioavailable because they contain specific dipeptides and tripeptides (like hydroxyproline-glycine) that can survive the digestive tract

Serious Adverse Reactions and When to Seek Medical Advice Whilst serious adverse reactions to vitamin B12 supplementation are exceptionally rare, elderly patients and their carers should be aware of warning signs that require immediate medical attention

[PubMed: 20520602] 95

Its short half-life, however, required it to be injected several times a day, which limited its appeal as a drug, and the company ran out of funding