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It is postulated that a salt bridge formed between Arg150 and Asp154, which replaces the salt bridge between Arg158 and Asp154, alters the conformation of Arg150, and, as a result, masks the receptor-binding region (residues 136150) (Wilson et al., 1994)

Emerging evidence suggests that ferritin light chain (FTL), ferritin heavy chain 1 (FTH1), and transferrin receptor (TFRC) are involved in iron storage, iron entry, and iron homeostasis [17]

doi: 10.1039/D1FO01237A 12