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APAP is metabolized to a toxic metabolite called N-acetyl-p-benzoquinone imine (NAPQI) that begins to accumulate in the cell, leading to mitochondrial dysregulation [15]

It has been reported that MOTS-c improves age-related insulin resistance in male mice by increasing glucose intake in soleus muscles (20)

doi: 10.1038/leu.2014.295 105 CuolloLDi CristofanoSSandomenicoAIaccarinoEOliverAZingoniAet al

Out of the three options, Thesis has an edge here because it uses some shorter lists of ingredients in doses that are sometimes lower than what human studies confirm to be effective