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297 With HD, senescent neural cells and neurons can arise because mutHTT contributes to chronic neuroinflammation via the secretion of SASP

Consistent with an oncogene effect, we found strikingly high levels of CBS, the enzyme that forms cystathionine and the rate-limiting enzyme in transsulfuration in the MYCN -amplified NB tumors

In a research setting, this is often done to minimize the number of injections

Additionally, it can delay gastric emptying and reduce food intake through central appetite suppression, ultimately leading to lower blood glucose levels