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Antibodies derived from patients or clinical source were identified, formulated and administered via inhalation to target the receptor-binding domain (RBD) of the virus, thereby blocking its interaction with angiotensin-converting enzyme 2 (ACE2) receptors, which are widely spread on human epithelium 37,38,39,40,41,42,43,44

In a related study, mice that were fed a high fat diet had crown-like signs of macrophage infiltrations, while mice that were given a high fat diet and injected with SOD3 had minimal signs of infiltrate (Cui et al., 2014)