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Summary Keywords microbiome-based interventions, probiotics, prebiotics, synbiotics, postbiotics, next-generation probiotics, microbiota-gut-brain axis (MGBA), neurodegenerative diseases (NDDs) Citation Auclair-Ouellet N, Kassem O, Bronner S, Oula M-L and Binda S (2025) Leveraging microbiome-based interventions to improve the management of neurodegenerative diseases: evidence for effects along the microbiota-gut-brain axis