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(2020) 15:e0226070

Chemical inhibition of IKK or its genetic knockout has become an effective method to block NF-B-mediated proliferation and migration of tumor cells and inflammatory response

Important markers such as myeloperoxidase, IL-1, TNF-, nitrates, superoxide dismutase and glutathione were measured in the bladder tissue

These pathways include TLR/NF- B, Bcl-2/caspase-9, PINK-Parkin, HIF-1 /VEGF, PI3K/Akt, and Nrf2 mentioned in the previous Section 2, which can promote neuroprotection by regulating these pathways (Bangar et al., 2024