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Following DNA damage, the cell cycle can be transiently arrested to allow for DNA repair or activation of pathways leading to programmed cell death (apoptosis) when the damage cannot be repaired (29)

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5.5 Abnormal Ovarian Enlargement In order to minimize the hazards associated with abnormal ovarian enlargement that may occur with GONAL-f therapy, individualize treatment and use the lowest effective dose [see Dosage and Administration (2.2, 2.3)]

Omega-3 has beneficial effects on the brain by increasing blood flow and reducing inflammation

It is possible that genetic deletions affecting a large number of cells may produce more pronounced compensatory effects during development masking the effects induced by the lack of GHR in the entire brain