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These include the quadriceps group, especially the vastus medialis and vastus lateralis, as well as the hamstrings, gastrocnemius, popliteus, and even the hip muscles such as the gluteus medius and hip adductors

Intriguingly, PIK3C3/VPS34 lactylation augments its interaction with Beclin1, Atg14L, and UVRAG, increasing its lipid kinase activity and promoting macroautophagy/autophagy and endolysosomal degradation

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