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Sodium hydroxide (NaOH), sodium chloride (NaCl), calcium chloride (CaCl 2 ), sodium dihydrogen phosphate dihydrate (NaH 2 PO 4 2H 2 O), disodium hydrogen phosphate dodecahydrate (Na 2 HPO 4 12H 2 O), potassium chloride (KCl), L-glucose (L-Glu), fructose (Fru), sucrose (Suc), L-ascorbic acid (AA), L-cysteine (L-Cys), L-arginine (L-Arg), and lactose (LAC) were obtained from Sinopharm Chemical Reagent Co., Ltd

MOTS-c is the third lever

JAMA 1979;241:2008

Unifying the hallmarks of major depression through neuroimmunemetabolicoxidative (NIMETOX) dysregulation: a mechanistic systems framework

It may be able to nudge the biochemical pathway away from producing dark eumelanin and toward producing lighter pheomelanin