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[36] [37] [38] A long-term study where vitamin B 12 was supplemented across a period of 10 years, led to lower levels of weight gain in overweight or obese individuals (p 20% of elderly individuals showed evidence of marginal vitamin B 12 depletion (serum vitamin B 12 : 148221 pmol/L)

Funding The work carried out in Torino was supported by the University of Torino, by an Assegno di Ricerca (AH) grant and by grants from the Istituto Giannina Gaslini (Genova, Italy) and the Compagnia SanPaolo (Turin, Italy) (FM)