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doi: 10.3389/fped.2014.00066

This study was approved by the Committee on the Ethics of Animal Experiments of East China Normal University

Altered skeletal muscle metabolic pathways, age, systemic inflammation, and low cardiorespiratory fitness associate with improvements in disease activity following high-intensity interval training in persons with rheumatoid arthritis

Once formed, AGEs can damage cellular structures through a number of mechanisms, including the formation of cross-links between key molecules of the basement membrane of the extracellular matrix and interaction with receptors on cell surfaces, leading to this way to alteration of cellular function [36, 37]