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10.1038/254531a0 97

Research Square Preprint2023 Apr 20

In this context, studies in germ-free and antibiotic-treated mice have contributed to the understanding of the relationship between intestinal microbiota and local and systemic homeostasis (174)

This then necessitates the addition of antioxidants such as vitamin E and ascorbic acid to maintain a stability between the generation of ROS and the readily available defensive antioxidants (Qamar et al., 2023)