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Moreover, GA has been shown to mitigate liver damage in rats exposed to dust, significantly reducing the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP), and altering the serum triglyceride (TG) levels, similar to the protective effects observed with PM2.5 exposure

In the first rodent proof-of-concept, local grafting of AD-MSCs into cyclophosphamide-injured ovaries restored follicle and corpus-luteum counts by secreting high levels of VEGF, IGF-1 and HGF, while male-cell tracking revealed the transplanted cells lodge mainly in the thecal layer rather than the germ line [172, 173]