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Journal of Lasers in Medical Sciences, 14, e22

Basak NP, Banerjee S

Parr MB

Transcriptomic interrogation of patient datasets shows NGF and TrkA expression enriched in osteosarcoma relative to other neurotrophins and receptors, with NGF associated with migratory and metastatic programs ( BDNF/TrkB signaling has been connected to malignant phenotypes across epithelial and neuroendocrine tumors and engages pathways that promote survival, invasion, and angiogenesis